1,4-dihydronicotinaMide riboside


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  • 1,4-dihydronicotinaMide riboside
  • 19132-12-8
  • C11H16N2O5
  • 256.26
  • White powder
  • 1kg/bag;25kg/drum
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Product name

1,4-dihydronicotinaMide riboside

Other name

1,4-DIHYDRONICOTINAMIDE RIBOSIDE

1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamide

SCHEMBL18849371

1-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE

CAS No.

19132-12-8

Molecular formula

C11H16N2O5

Molecular weight

256.26

Purity

98%

Appearance

White powder

Packing

1kg/bag;25kg/drum

Application

Dietary supplement raw materials

 

 1. Product introduction

1,4-dihydronicotinamide riboside, also known as NRH.The reduced form of NRH is a potent NAD+ precursor that helps to replenish its levels in the cell.

First and foremost, it is important to understand the role of NAD+ in the body. NAD+ is a coenzyme that is involved in numerous cellular processes, including energy metabolism, DNA repair, and gene expression. As we age, our levels of NAD+ decline, which has been implicated in the aging process and age-related diseases. This has led to a growing interest in identifying molecules that can boost NAD+ levels in the body, and 1,4-dihydronicotinamide riboside is one such molecule.

1,4-dihydronicotinamide riboside is a potent NAD+ precursor, and research has shown that it can effectively raise NAD+ levels in cells. This has led to speculation that 1,4-dihydronicotinamide riboside supplementation could have therapeutic potential in a wide range of health conditions, including metabolic disorders, neurodegenerative diseases, and aging-related decline.

In fact, there is evidence to suggest that 1,4-dihydronicotinamide riboside may be even more effective than its parent molecule, nicotinamide riboside, at increasing NAD+ levels. This is because 1,4-dihydronicotinamide riboside is a more potent reducer, meaning it is better at donating electrons to the NAD+ synthesis pathway. As a result, it has the potential to more efficiently fuel cellular NAD+ production.

In addition to its role in NAD+ biosynthesis,1,4-dihydronicotinamide riboside also possesses antioxidant properties. Oxidative stress, which results from an imbalance between free radicals and antioxidants in the body, is implicated in numerous diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. By scavenging free radicals and reducing oxidative damage,1,4-dihydronicotinamide riboside may offer additional health benefits beyond its role as an NAD+ precursor.

 

2. Feature

 (1) High purity: 1,4-dihydronicotinamide riboside can obtain high-purity products through refined manufacturing processes. High purity means better bioavailability and fewer adverse reactions.

 (2) Safety: 1,4-dihydronicotinamide riboside is a natural product that has been proven to be safe for the human body. Within the dosage range, there are no toxic side effects.

 (3) Stability: 1,4-dihydronicotinamide riboside has good stability and can maintain its activity and effect under different environments and storage conditions.

 

3. Applications

 1,4-Dihydronicotinamide is the reduced form of nicotinamide riboside. It can exist in both oxidized and reduced forms and is a precursor to the newly discovered NAD (nicotinamide adenine dinucleotide), available as a supplement, with NRH being a more potent and faster NAD+ precursor than NR.

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